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Thus, oxidative stress in COPD not only reflects the burden of local and systemic damage but also establishes a common pathological foundation for the subsequent activation of various regulated cell death modalities via mtROS accumulation, inhibition of antioxidant defenses, and DAMP release ( Figure 3 )

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Existing clinical observations indicate that dietary antioxidants demonstrate certain therapeutic effects in uterine fibroid patients, and supplementing key nutrients (such as vitamin C and vitamin D) can play an adjunctive role [190]