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Stimulatory nanoparticles can reprogramme antigen-presenting cells and enhance T-cell activation, as demonstrated in the 4T1 model [142]

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Andl and colleagues [35] generated transgenic mice having epidermal basal cell-specific ectopic expression of Dickkopf 1 (DKK1), which inhibits Wnt action [36,37,38,39,40] by binding with LRP co-receptor, to evaluate the role of Wnt in HF